6th Workshop on
Biomedical and Bioinformatics Challenges for Computer Science (BBC 2013)



held in conjunction with

International Conference on Computational Science (ICCS 2013)

Barcelona, Spain

June 5 - June 7, 2013





Emerging technologies in genomics, proteomics, interactomics and other life science areas are generating an increasing amount of complex data and information. The evolving data and information ecosystem includes large experimental �omics� data sets, natural language text from the scientific literature and the Web, and highly connected heterogeneous information networks, such as open linked data distributed on the Internet. Integrating and analysing this information in the context of modern life science research problems and biomedical applications poses a considerable challenge for bioinformatics and computational biology. Traditionally, bioinformatics has concentrated on methods and technologies facilitating the acquisition, storage, organization, archiving, analysis and visualization of biological and medical data. Computational biology, on the other, hand, has emphasized mathematical and computational techniques facilitating the modelling and simulation of biomedical processes and systems. In recent years the distinction between these two fields has become increasingly blurred. In order to tackle the growing complexity associated with emerging and future life science challenges, bioinformatics and computational biology researchers and developers need to explore, develop and apply novel computational concepts, methods, tools and systems. Many of these new approaches are likely to involve advanced and large-scale computing techniques, technologies and infrastructures such as:

      High-performance architectures and systems (e.g., multicore, GPU);

      Distributed computing (e.g. grid, cloud, peer-to-peer, Web services, e-infrastructures);

      Data and information management and integration (e.g., databases, data warehousing, data fusion);

      Knowledge discovery/management (e.g., knowledge bases, data mining, ontologies, workflow);

      Computational simulation (mechanistic, stochastic, multi-model);

      Artificial and computational intelligence (machine learning, agents, evolutionary techniques).


Together, these topics cover the key bioinformatics and computational biology techniques and technologies encountered in modern life science environments: (1) Advanced computing architectures/infrastructures; (2) Data/information management and integration; (3) Data/information analysis and knowledge discovery; (4) Integration of quantitative/symbolic knowledge into executable biomedical �theories� or models. The aim of this workshop is to bring together computer and life scientists to discuss emerging and future directions in these areas.

This is the 6th edition of this workshop, which was previously held in Krak�w (2008), Baton Rouge (2009), Amsterdam (2010), Singapore (2011), and Omaha (2012). �This 6th edition has been modified to incorporate the advanced and large-scale bioinformatics and computational biology challenges associated with executable �theories� or models.



The workshop is seeking original research contributions presenting innovative bioinformatics and computational biology concepts and solutions in the areas outline above. The topics of interest include but are not limited to the following:


Computer Science


Computational Biology

       Dedicated hardware & architectures

       High performance & distributed computing

       Parallelisation techniques

       Grid/cloud computing


       Volunteer computing

       Peer-to-peer computing

       (Distributed) workflows


       Data management/integration/fusion

       Biological sequence & structure analysis

       Genomics, proteomics, metabolomics, interactomics, etc.

       Analysis of biological networks

       Biomedical image analysis


       Data visualization

       Data mining & knowledge discovery

       Simulation of biological systems/processes

       Multi-model approaches

       Systems biology

       Knowledge-based techniques

       Knowledge management

       Artificial / computational intelligence techniques

       Executable theories and models



The manscripts submitted to this workshop must be camera-ready and formatted according to the rules of Procedia Computer Science (http://www.elsevier.com/wps/find/journaldescription.cws_home/719435/description). Please use this file for a Latex template plus instructions (http://www.iccs-meeting.org/iccs2013/procedia/ecrc-procs.zip) and click here for an MS word template file (http://www.iccs-meeting.org/iccs2013/procedia/ProcediaComputerScience_template.dot). Submission implies the willingness of at least one of the authors to register and present the paper at the workshop. PostScript and source versions of your paper must be submitted electronically through the paper submission system (http://www.iccs-meeting.org/iccs2013/papers/upload.php) indicating the workshop title


6th Workshop on Biomedical and Bioinformatics Challenges for Computer Science (BBC 2013)


A copyright form (http://www.iccs-meeting.org/iccs2013/procedia/ProcediaComputerScience_copyrightform.doc) is only needed after the paper has been accepted for publication in the proceedings. Please, note that papers must not exceed ten pages in length, when typeset using the Procedia format. Dates of deadlines for manuscript submission (full paper), notification of acceptance, deadline for camera-ready paper submission and registration may be found in the Important Dates (http://www.iccs-meeting.org/iccs2013/important-dates.html) section of the ICCS Web site, unless otherwise specified on this workshop site.


Manuscripts submitted to this workshop must be based on unpublished, mature and original work and must be submitted to ICCS only.


ICCS is an ERA 2010 A-ranked conference series.



After the workshop, selected papers may be invited for a special issue of the Journal of Computational Science. Selected papers (extended and revised version) accepted on the 1st edition of this workshop have been published on a special section of Future Generation Computer Systems, Elsevier.



Full papers submission:���������������������� January 2, 2013 (EXTENDED) December 15, 2012

Notification of acceptance:����������� February 10, 2013

Camera-ready papers: ����� ����������� March 1, 2013

Authors registration: ����������������� February 10 - March 10, 2013

Participant early registration: ������ February 10 - April 25, 2013

Tutorials, welcome reception: ����� June 4, 2013

Conference/Workshop sessions: �� June 5 - June 7, 2013




Mario Cannataro, University Magna Gr�cia of Catanzaro, Italy

Werner Dubitzky, University of Ulster, United Kingdom

Joakim Sundnes, Simula Research Laboratory, Norway

Rodrigo Weber dos Santos, Federal University of Juiz de Fora, Brazil



1.     Dave Angulo, DePaul University, Chicago, USA

2.     Francisco Azuaje, CRP-Sant�, Luxembourg

3.     Daniel Berrar, Tokyo Institute of Technology, Tokyo, Japan

4.     Eun Bo Shim, Kangwon National University, Chuncheon, Republic of Korea

5.     Rui Brito, University of Coimbra, Portugal

6.     Kevin Burrage, University of Oxford, Oxford, United Kingdom

7.     Nagasuma Chandra, Indian Institute of Science, Bangalore, India

8.     Bastien Chopard, University of Geneva, Geneva, Switzerland

9.     Tim Clark, Harvard Medical School, USA

10.   Attila Csik�sz-Nagy, King�s College London, UK, and Fondazione Edmund Mach, Trento, Italy

11.   Giuseppe Di Fatta, University of Reading, UK

12.   Christine Froidevaux, LRI-Bioinformatics Group - University Paris XI, Orsay, France

13.   Alan Garny, University of Oxford, Department of Physiology, Anatomy & Genetics

14.   Concettina Guerra, University of Padova, Italy

15.   Pietro Hiram Guzzi, University Magna Gr�cia of Catanzaro, Italy

16.   Ulrich Hansmann, Research Centre Juelich, Germany

17.   Karl Helmer, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, USA

18.   Vicente Hern�ndez, Univ. Polit�cnica de Valencia, Spain

19.   Pilar Herrero, Universidad Polit�cnica de Madrid, Madrid, Spain

20.   Alfons Hoekstra, University of Amsterdam, Amsterdam, The Netherlands

21.   Ela Hunt, Bundesamt f�r Statistik BFS / Office Federal de la Statistique OFS, Switzerland

22.   Glenn Terje Lines, Simula Research Laboratory, Norway

23.   Marcelo Lobosco, Federal University of Juiz de Fora, Brazil

24.   Uko Maran, University of Tartu, Estonia

25.   Wagner Meira Jr., Federal University of Minas Gerais, Brazil

26.   Maria Mirto, University of Salento, Italy

27.   Hartmut Mix, University of Technology Dresden, Germany

28.   Igor Mozetič, Jo�ef Stefan Institute, Ljubljana, Slovenia

29.   Salvatore Orlando, University of Venezia, Italy

30.   Mar�a S. P�rez, Universidad Polit�cnica de Madrid, Madrid, Spain

31.   Gernot Plank, University of Graz, Austria

32.   Omer F. Rana, Cardiff University, UK

33.   Osbaldo Resendis-Antonio, Instituto Nacional de Medicina Genomica, (INMEGEN), M�xico

34.   Blanca Rodriguez, University of Oxford, UK

35.   Insik Shin, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea

36.   Luis Paulo da Silva Barra, Federal University of Juiz de Fora, Brazil

37.   Fabrizio Silvestri, ISTI-CNR, Italy

38.   Raymond Spiteri, University of Saskatchewan, Canada

39.   Martin Swain, Aberystwyth Universith, Aberystwyth, United Kingdom

40.   Roberto Tagliaferri, University of Salerno, Italy

41.   El-Ghazali Talbi, Universit� des Sciences et Technologies de Lille, France

42.   Paolo Trunfio, University of Calabria, Italy

43.   Pierangelo Veltri, University Magna Gr�cia of Catanzaro, Italy

44.   Edward J. Vigmond, University of Calgary, Canada

45.   Jordi Vill� i Freixa, Universitat de Vic, Vic, Spain

46.   Giovanni Vozzi, University of Pisa, Pisa, Italy

47.   Chong Wang, Technical University of Wildau, Wildau, Germany

48.   Huiru Zheng, University of Ulster, Jordanstown, United Kingdom

49.   Albert Zomaya, University of Sydney, Australia

50.   Bla� Zupan, University of Ljubljana, Ljubljana, Slovenia